Ultra Market Research | United States Migraine Market
Illustration of migraine treatment options in the United States healthcare market, featuring pharmaceuticals, patient care, and therapy pathways (2024–2030).

United States Migraine Market

  • Report ID : 1080

  • Category : United-States(US)

  • No Of Pages : 134

  • Published on: April 2025

  • Status: Published

  • Format : Power Point PDF Excel Word

Key Question Answer

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Global Market Outlook

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In-depth analysis of global and regional trends

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Analyze and identify the major players in the market, their market share, key developments, etc.

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To understand the capability of the major players based on products offered, financials, and strategies.

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Identify disrupting products, companies, and trends.

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To identify opportunities in the market.

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Analyze the regional penetration of players, products, and services in the market.

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Comparison of major players financial performance.

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Evaluate strategies adopted by major players.

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Recommendations

United States Migraine Market

Introduction

The US migraine market includes the development, approval, and sale of drugs intended to treat and prevent migraines, a neurological disorder characterized by frequent, disabling headache with or without nausea, vomiting, and photo- and phonosensitivity. Current trends reflect a profound movement towards biologic therapies, specifically CGRP (calcitonin gene-related peptide) inhibitors, that have shown effectiveness in both the acute and preventive treatment of migraines. The market value was around USD 2.09 billion in 2023 and is expected to achieve USD 4.66 billion by 2030 with a compound annual growth rate (CAGR) of 12.1% from 2024 to 2030 citeturn0search0. The growth is based on rising prevalence of migraines, technology advancements in treatment, and an increased awareness level among healthcare professionals and patients.

 

Segmentation

Acute Treatment

Oral Medications

Triptans
NSAIDs
Others

Injectables

CGRP Inhibitors
DHE (Dihydroergotamine)
Others

Nasal Sprays

CGRP Antagonists
Others

Others

 

Preventive Treatment

Oral Medications

Beta-blockers
Antidepressants
Anticonvulsants
Others

Injectables

CGRP Monoclonal Antibodies
Botox
Others
Devices

Neuromodulation Devices
Others
Others

By Age Group

Pediatric

Acute Treatment
Preventive Treatment

Adult

Acute Treatment
Preventive Treatment
Geriatric

Acute Treatment
Preventive Treatment

By Distribution Channel

Hospital Pharmacies
Retail Pharmacies
Online Pharmacies
Others

 

    List of Market Players

GlaxoSmithKline (UK)
Pfizer Inc. (USA)
AbbVie Inc. (USA)
Amgen Inc. (USA)
Eli Lilly and Co. (USA)
Teva Pharmaceutical Industries Ltd. (Israel)
Biohaven Ltd. (USA)
Johnson & Johnson (USA)
Bausch Health Companies Inc. (Canada)
Axsome Therapeutics (USA)
Novartis AG (Switzerland)
Merck & Co. (USA)
Allergan (USA)
Zogenix (USA)
Alder BioPharmaceuticals (USA)

 

Drivers

The United States migraine market is driven by a number of factors, such as the high incidence of migraines with around 12% of the population being affected. Improved treatment options, specifically the discovery of CGRP inhibitors like Aimovig, Ajovy, and Vyepti, have offered effective substitutes for conventional therapies citeturn0news13. Furthermore, rising awareness and enhanced diagnostic methods have resulted in improved detection and treatment of migraine patients. The increase in telehealth services and direct-to-consumer platforms, like Pfizer's Zavzpret, have also increased patient access to treatments citeturn0news14 In addition, the increased awareness of the economic and social burden of migraines has triggered investment in research and development, driving market growth.

 

Restraints

In spite of its expansion, the US migraine market has issues, such as the prohibitive price of new products, which can restrict patient access and insurance coverage. Stigma towards migraine as a valid medical illness can cause underdiagnosis and undertreatment. Racial inequities in access to healthcare and treatment outcomes are also challenges to the market environment, with disadvantaged communities receiving inferior care citeturn0news22. Moreover, regulatory challenges and the requirement of long periods of clinical testing before new drugs can be licensed can slow new therapies reaching the marketplace.

 

Opportunity

The U.S. migraine market offers many opportunities, especially in the creation of personalized medicine and combination therapies that are tailored to the needs of individual patients. The growing use of digital health solutions, such as mobile apps for symptom monitoring and virtual consultations, provides new opportunities for patient management and engagement. Increasing access to treatments through insurance reforms and patient assistance programs can increase market penetration. In addition, bridging healthcare disparities and providing equal access to treatment has the potential to unlock untapped population segments, fueling market growth.

 

 

Trend

One of the trends in the U.S. migraine market is the increasing tendency towards the use of CGRP inhibitors as initial-line treatments to replace traditional medicines such as antidepressants and beta-blockers. These biologic drugs provide site-specific action with enhanced efficacy and less side effects citeturn0news13. The approval of combination therapies like Axsome Therapeutics' Symbravo, which is a combination of meloxicam and rizatriptan, indicates a tendency towards multi-spectrum treatment strategy citeturn0news21. Also, the integration of telemedicine platforms for prescription and management is revolutionizing patient convenience and access, in line with wider healthcare digitalization trends.

 

    Approved Products

Aimovig (Erenumab)
Ajovy (Fremanezumab)
Emgality (Galcanezumab)
Vyepti (Eptinezumab)
Nurtec (Rimegepant)
Ubrelvy (Ubrogepant)
Qulipta (Atogepant)
Zavzpret (Zavegepant)
Symbravo (Meloxicam + Rizatriptan)

 

 

    Key Target Audience

Pharmaceutical Companies
Healthcare Providers (Neurologists, General Practitioners)
Insurance Providers
Regulatory Bodies (FDA, CDC)
Research Institutions
Telehealth Platforms
Patients and Patient Advocacy Groups
Market Research Firms
Investors and Venture Capitalists
Healthcare Policy Makers

The United States migraine market was valued at approximately USD 2.09 billion in 2023 and is projected to grow significantly, reaching around USD 4.66 billion by 2030.
Key drivers include rising migraine prevalence, advancements in CGRP-based therapies, growing awareness, telehealth adoption, and increased R&D investment in migraine-specific treatments.
Acute treatment, particularly oral and injectable CGRP inhibitors, currently dominates the market due to their high efficacy and patient preference
Major restraints include high treatment costs, insurance coverage limitations, racial healthcare disparities, and regulatory hurdles for new drug approvals.
Key companies include Pfizer Inc., Amgen Inc., AbbVie, Eli Lilly, Biohaven, Teva Pharmaceuticals, and Novartis, among others.

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