Ultra Market Research | United States(U.S.) Genomics Market

United States(U.S.) Genomics Market

  • Report ID : 621

  • Category : Biotechnology,United-States(US)

  • No Of Pages : 140

  • Published on: August 2024

  • Status: Published

  • Format : Power Point PDF Excel Word

Key Question Answer

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Global Market Outlook

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In-depth analysis of global and regional trends

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Analyze and identify the major players in the market, their market share, key developments, etc.

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To understand the capability of the major players based on products offered, financials, and strategies.

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Identify disrupting products, companies, and trends.

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To identify opportunities in the market.

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Analyze the regional penetration of players, products, and services in the market.

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Comparison of major players financial performance.

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Evaluate strategies adopted by major players.

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Recommendations

United States (U.S.) Genomics Market
Estimated at US$ XX billion in 2023, the U.S. genomics industry is projected to reach around US$ XX billion by 2033, with a compound annual growth rate (CAGR) of XX% from 2024 to 2033. The study of a person's complete genetic composition and how it interacts with other genes and the environment is known as genomics, and it is thriving in the large and varied healthcare system in the United States. The nation is well-known in this subject because to renowned research facilities, a large number of noteworthy genomics projects, and prominent individuals. In addition, the considerable and well-established healthcare sector in the United States keeps developing due to the country's increasing population.
The expansion of healthcare and genomic advancements are mutually reinforcing, which drives the growth trajectory of the U.S. genomics market.

Market Overview
Growing understanding of an organism's entire genome and its interactions with its surroundings is driving the rapid rise of the U.S. genomics sector. States that require genetic screening for newborns—of which 95% of them do—highlight the importance of this industry. However, because newborn screening is governed at the state level, testing criteria differ by location. The Human Genome Project (HGP), an endeavor spearheaded by the US government and which resulted in the first full sequencing of a human genome in 2000, was completed, marking a significant turning point in the field of genomics.
Thanks to developments, it is now possible to sequence a person's entire genome in less than 24 hours for a reasonable price, giving customers access to DNA sequences that show their ethnic heritage. Beyond the field of medicine, genomics finds use in anthropology, biotechnology, agriculture, and other social sciences. This broad range of applications contributes to the field's explosive expansion and diverse effects on a variety of businesses.
 

Report Highlights     
By Application & Technology
Market is dominated by the functional genomics segment, which is driven by improvements in drug discovery made possible by functional genomics techniques. By identifying possible therapeutic targets, this method makes it easier to investigate the impact of genes and how they relate to illnesses. Of all the tools out there, CRISPR/Cas9 is the most potent and adaptable gene editing instrument. By analyzing gene function and regulation within dynamic systems using genomic and omic data, functional genomics provides important new understandings into the effects of genetic variants on health and disease. Functional genomics with CRISPR/Cas9 technology spurs innovation in drug discovery and treatment development, driving market growth with its capacity to clarify biological processes at the molecular level.
With genomics expected to increase at a significant rate in the near future, pathway analysis appears to be a leader in this regard. The availability of next-generation sequencing is expanding, which makes it a good time to review approaches for pathway-based analysis of genomic data. Pathway analysis techniques are essential to life sciences research because they use statistical tests and algorithms along with biomolecular understanding to extract biological relevance from high-throughput biological data. Even with their extensive use, the fundamentals of pathway analysis require ongoing improvement in order to stay up with the rapidly changing needs of data analysis and genomic research.

By Deliverable
With the highest stake in the US genomics market, the goods segment continues to cement its dominance. This category includes a wide range of items, including plastic products, PCR reagents, real-time PCR systems, heat cyclers, NGS library prep kits, ddPCR, and ddSEQ Systems. Notably, the product lines offer a wide variety of reagents specifically designed for PCR, real-time PCR, and reverse transcription that have been painstakingly refined to produce reliable and precise results. Furthermore, the section plays a crucial role in enabling genomic research and applications because experimentally verified PCR primer and probe assays support a variety of investigations, such as copy number variation, gene expression, and mutation detection.
In the U.S. genomics market, services are expected to increase at the second-fastest rate behind goods, which continue to lead the market. Whole genome sequencing, whole exome sequencing, targeted panel sequencing, shotgun metagenomics, and 16S rRNA gene sequencing are just a few of the services that fall under this category. Notably, the Genomics Services Laboratory (GSL) has more than ten years of experience in the creation and interpretation of next-generation sequencing (NGS) data.
GSL provides all-inclusive assistance for NGS, including library preparation, sequence production, data analysis, and experimental design. GSL is a major provider of genomics services in the industry because it effectively analyzes complicated sequencing datasets, including integrated DNA and RNA sequence data, by utilizing advanced bioinformatics skills.


By End-Use
With the biggest market share in the US genomics market, pharmaceutical and biotechnology businesses are the main end customers. Because it allows firms to design safer, more effective therapies that target the underlying disease directly rather than just its symptoms, genomics plays a critical role in modernizing the drug development process. Genomics enables the discovery of potential repurposing opportunities for existing medications that have been shown to be safe in people and approved for use in various settings by identifying the underlying causes of diseases within a genomic framework.
This deliberate use of genetics into medication development procedures highlights how important it is to enhance overall patient outcomes and spur innovation in the biotechnology and pharmaceutical industries.
The clinical research industry in the United States is poised for substantial expansion. By utilizing genomes, clinical researchers can obtain very efficient diagnostic probes that can identify hereditary features and frequently prevent symptoms from arising. Recent developments in genomics provide new approaches to the diagnosis of diseases at the DNA, RNA, and bioactive protein levels, enabling more thorough disease detection.
 Furthermore, technologies similar to those used in the production of microcircuits can be used to mechanize genomic approaches, allowing for the simultaneous screening of thousands of disorders utilizing microarrays. In addition to improving disease diagnosis, this thoughtful incorporation of genetics into clinical research spurs innovation and advances the industry's growth trajectory.

Market Dynamics
Driver 
Genomic Medicine Revolutionizes Healthcare 
Combination of genomics and DNA sequencing in medicine provides a wealth of information about the molecular biology of individuals, revealing genetic variations and mutations that guide individualized treatment regimens. This move away from a one-size-fits-all strategy and toward customized care based on each patient's unique genetic makeup has enormous potential for use in all phases of healthcare, including diagnosis, treatment, and prevention. With the ability to diagnose conditions more quickly and accurately and provide patients with individualized treatment for genetic diseases and cancer, genomic medicine has become increasingly popular in a number of fields, including prenatal care, cancer, pharmacology, uncommon diseases, and infectious diseases.
Healthcare progress is further propelled by the acceptance of precision medicine and the use of genomes to optimize drug administration. It is anticipated that these developments would open the door for new technologies, such as cancer vaccine centers and related studies, which will spur expansion in the US genomics sector.
 

Restraints
Complex Ethical, Legal, and Social Implications 
With the introduction of genomics come a plethora of complex legal, social, ethical, and economic issues, in addition to worries about potential risks and hazards. Concerns about privacy violations, social stigma, and possible exploitation of genetic data are relevant, especially in light of the possibility of creating a genetic underclass that could be denied health insurance due to results of genetic testing. Concerns are heightened by issues with DNA sequence intellectual property rights and the use of populations in developing nations for genetic databases, frequently at the request of businesses in the rich world.
The lack of strong international intellectual property laws widens the divide between industrialized and developing nations, which limits the possibility for growth in the U.S. genomics market.

Opportunities 
Advancements in Genomics 
Even though genomics is complicated and it can be difficult to foresee its full health effects since gene products interact in complex ways, poor nations have a lot of potential to concentrate on taking immediate steps to improve public health and healthcare systems. The human genome sequencing project, in conjunction with the continuing and projected advancements in genomics, offers a once-in-a-lifetime chance to improve our comprehension of the role that genetics plays in human health and disease.
This new understanding makes it possible to distinguish non-genetic impacts more precisely and speeds up the application process for illness prevention, diagnosis, and therapy. These developments put the U.S. genomics market at the forefront of revolutionary healthcare solutions by fostering growth and innovation.

Recent Developments

•    In May 2024, SOPHiA GENETICS launched new whole genome sequencing capabilities.
•    In October 2023, Complete Genomics demonstrated technical and commercial momentum in the sequencing market through new customers, partnerships, and collaborations within one year of launching in the U.S.
•    In January 2024, Ultima Genomics announced the end of early access and the upcoming launch of UG 100.
•    In August 2023, PacBio and GeneDx launched a research collaboration with the University of Washington to study long-read whole genome sequencing for increased diagnostic yield in neonatal care.
•    In February 2024, Veracyte completed the acquisition of C2i Genomics.

Key Players in the U.S. Genomics Market
Illumina Inc.
Thermo Fisher Scientific Inc.
Agilent Technologies
Luminex Corporation
Myriad Genetics Inc.
BGI Genomics Co. Ltd.
Bio Rad Laboratories Inc.
Caris Life Sciences
Danaher Corp.
Eurofins Scientific SE

 

Market Segmentation
Application & Technology Outlook 
Functional Genomics
Transfection
Real-Time PCR
RNA Interference
Mutational Analysis
SNP Analysis
Microarray Analysis
Epigenomics
Bisulfite Sequencing
Chromatin Immunoprecipitation (ChIP & ChIP-Seq)
Methylated DNA Immunoprecipitation (MeDIP)
High-Resolution Melt (HRM)
Chromatin Accessibility Assays
Microarray Analysis
Pathway Analysis
Bead-Based Analysis
Microarray Analysis
Real-time PCR
Proteomics Tools (2-D PAGE; yeast 2-hybrid studies)
Biomarker Discovery
Mass Spectrometry
Real-time PCR
Microarray Analysis
Statistical Analysis
Bioinformatics
DNA Sequencing
Others
Deliverables Outlook 
Products
Instruments/Systems/Software
Consumables & Reagents
Services
NGS-based Services
Core Genomics Services
Biomarker Translation Services
Computational Services
Others
End-use Outlook 
Clinical Research
Academic & Government Institutes
Hospitals & Clinics
Pharmaceutical & Biotechnology Companies
Other End-users

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