Ultra Market Research | Global Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Market
Global ATTR-CM Market Analysis - Trends, Innovations, and Growth Prospects in Cardiomyopathy Care

Global Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Market

  • Report ID : 852

  • Category : Pharmaceuticals,Global

  • No Of Pages : 165

  • Published on: November 2024

  • Status: Published

  • Format : Power Point PDF Excel Word

Key Question Answer

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Global Market Outlook

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In-depth analysis of global and regional trends

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Analyze and identify the major players in the market, their market share, key developments, etc.

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To understand the capability of the major players based on products offered, financials, and strategies.

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Identify disrupting products, companies, and trends.

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To identify opportunities in the market.

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Analyze the regional penetration of players, products, and services in the market.

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Comparison of major players financial performance.

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Evaluate strategies adopted by major players.

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Recommendations

Global Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Market

Introduction

The global ATTR-CM market encompasses the diagnosis, treatment, and management of transthyretin amyloid cardiomyopathy, a progressive and life-threatening disease caused by misfolded transthyretin proteins depositing in heart tissue. ATTR-CM is primarily classified into hereditary (hATTR) and wild-type (wtATTR) forms, affecting cardiac function. The growing awareness of this rare condition and advancements in diagnostic tools and therapeutics have significantly impacted the market's growth. Key applications include ATTR-CM drug development, targeted therapies, and cardiac imaging techniques. With increased prevalence, particularly among aging populations, and expanded research into amyloidosis solutions, the global ATTR-CM market is forecast to grow substantially. Recent market trends indicate a rise in the development of novel therapies and an active drug pipeline, positioning the market for significant expansion.

 

Segmentation

  • By Treatment Type
  • Pharmacological Therapies
    • Tafamidis
    • Diflunisal
    • Non-steroidal anti-inflammatory Drugs (NSAIDs)
    • Others
  • Gene Silencing Therapies
    • Patisiran
    • Inotersen
  • Supportive Therapies
    • Beta-Blockers
    • Diuretics
    • Anti-arrhythmic Drugs

 

  • By Diagnostics
  • Imaging Techniques
    • Echocardiography
    • Cardiac MRI
    • Nuclear Imaging
    • Others
  • Biomarker Testing
    • NT-proBNP Testing
    • Troponin Testing
    • Others
  • Genetic Testing
    • Mutation Analysis
    • Family History Testing

 

  • By End-User
  • Hospitals and Clinics
    • Cardiology Departments
    • Specialty Clinics
  • Diagnostic Laboratories
    • Independent Laboratories
    • Hospital-Affiliated Labs
  • Research and Academic Institutes

 

  • By Distribution Channel
  • Hospital Pharmacies
    • Inpatient Dispensing
    • Specialty Drug Distribution
  • Retail Pharmacies
    • Chain Pharmacies
    • Standalone Pharmacies
  • Online Pharmacies

 

  • By Geography

North America
United States
Canada


Europe
Germany
France
United Kingdom

Rest of Europe


Asia Pacific
China
Japan
India

Southeast Asia
Rest of Asia Pacific


Latin America
Brazil
Rest of Latin America

 

Middle East & Africa (MEA)
GCC
North Africa
South Africa
Rest of Middle East & Africa

 

List of Market Players

  1. Pfizer Inc. (United States)
  2. Alnylam Pharmaceuticals (United States)
  3. Eidos Therapeutics (United States)
  4. Ionis Pharmaceuticals (United States)
  5. BridgeBio Pharma (United States)
  6. AstraZeneca (United Kingdom)
  7. GlaxoSmithKline (United Kingdom)
  8. Johnson & Johnson (United States)
  9. Novartis AG (Switzerland)
  10. Sanofi (France)
  11. Prothena Corporation (United States)
  12. Regeneron Pharmaceuticals (United States)
  13. Merck & Co. (United States)
  14. Amgen Inc. (United States)
  15. Bristol-Myers Squibb (United States)

 

Drivers

The global ATTR-CM market is driven by increasing disease awareness, advancements in diagnostic capabilities, and a robust drug pipeline. Early detection of ATTR-CM through imaging techniques and biomarker testing has become a critical factor in improving patient outcomes, driving market demand for advanced diagnostic tools. The aging population, particularly in developed regions, has contributed to a rise in ATTR-CM prevalence, creating a strong need for effective treatment solutions. Pharmaceutical companies are actively investing in research to develop innovative therapies targeting transthyretin stabilization and gene silencing. Additionally, collaborations between research institutes and industry stakeholders have accelerated drug approvals, further fueling market growth.

 

Restraints

Despite significant progress, the ATTR-CM market faces challenges, including the high cost of therapies and limited accessibility to diagnostic tools in low-income regions. Many patients remain undiagnosed due to the disease's rarity and overlapping symptoms with other cardiac conditions, delaying appropriate treatment. Regulatory hurdles and lengthy approval processes for novel drugs also restrict market growth. Limited awareness among healthcare providers about the latest diagnostic and therapeutic advancements compounds these challenges.

 

Opportunity

The ATTR-CM market holds substantial growth potential, particularly in emerging economies where improved healthcare infrastructure can facilitate earlier diagnoses and treatment. Innovations in gene editing and RNA-based therapies offer promising opportunities to address the underlying genetic causes of hATTR. The growing use of artificial intelligence in cardiac imaging and biomarker analysis can enhance diagnostic accuracy, creating avenues for market expansion. Additionally, pharmaceutical companies are exploring combination therapies and expanding their focus on precision medicine, tailored to individual patient profiles, further driving the market forward.

 

Trend

The ATTR-CM market is witnessing a surge in gene silencing technologies such as RNA interference (RNAi) and antisense oligonucleotides, transforming the treatment landscape. AI integration in diagnostics is enabling more precise detection of ATTR-CM through advanced imaging analytics. Collaboration between biotech firms and research institutions is accelerating innovation in transthyretin amyloidosis therapies. The rise of telemedicine platforms is also facilitating early consultations and screenings, particularly in remote areas.

 

Approved Products and Pipeline

Approved Products: Tafamidis (Vyndaqel, Vyndamax), Patisiran (Onpattro), Inotersen (Tegsedi).
Pipeline/Reg/Pre-Reg Products: Eplontersen, Vutrisiran, AG10.

 

Key Target Audience

  • Cardiologists and Healthcare Providers
  • Hospitals and Specialty Clinics
  • Diagnostic Laboratories
  • Pharmaceutical and Biotechnology Companies
  • Academic and Research Institutes
  • Healthcare Policy Makers

 

FAQs about the Global ATTR-CM Market

Transthyretin amyloid cardiomyopathy is a condition caused by the accumulation of misfolded transthyretin protein in the heart.
Rising disease prevalence, advancements in diagnostics, and innovative therapeutic development.
Cardiac imaging (MRI, echocardiography), biomarker tests, and genetic testing.
Pfizer, Alnylam Pharmaceuticals, and Eidos Therapeutics are among the market leaders.
Gene silencing therapies, AI-enabled diagnostics, and telemedicine adoption are key trends.

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