Ultra Market Research | Biomarkers Market Overview
Biomarkers Market Overview
Report ID : 592
Category : Pharmaceuticals
No Of Pages : 145
Published on: July 2024
Status: Published
Format :
Key Question Answer
Global Market Outlook
In-depth analysis of global and regional trends
Analyze and identify the major players in the market, their market share, key developments, etc.
To understand the capability of the major players based on products offered, financials, and strategies.
Identify disrupting products, companies, and trends.
To identify opportunities in the market.
Analyze the regional penetration of players, products, and services in the market.
Comparison of major players financial performance.
Evaluate strategies adopted by major players.
Recommendations
Biomarkers Market Overview The global biomarkers market was valued at approximately US$ XX billion in 2023 and is projected to reach around US$ XX billion by 2033, with a compound annual growth rate (CAGR) of XX% from 2024 to 2033. Biomarkers play a crucial role in advancing drug development and biomedical research, helping to deepen our understanding of the relationship between biological processes and clinical outcomes. The FDA's support for using biomarkers in both basic and clinical research, along with the development of new biomarkers as potential surrogate endpoints, emphasizes their growing importance. Biomarkers can accelerate drug development, reduce exposure to ineffective treatments, and improve our understanding of healthy physiology. However, there are significant risks, especially when trial designers mistakenly use biomarkers as clinical endpoints. Despite these challenges, the benefits of biomarkers are driving significant market growth, highlighting their critical role in the evolving landscape of medical research and drug development.
Market Overview The biomarkers market is growing rapidly due to their essential role as objective measures of cellular or organismal states at specific times. Biomarkers include both routine measurements, like blood pressure or body weight, and advanced tests of blood, urine, or tissues. They act as early health warning systems and help clarify the complex interactions between environmental exposures, human biology, and disease. Their widespread use in research and clinical practice has normalized their use as primary endpoints in clinical trials, especially when well-characterized biomarkers consistently predict relevant clinical outcomes across diverse treatments and populations. Continuous validation of biomarkers is necessary to ensure their accuracy. Biomarkers are used for disease prevention and detection, individual risk assessment, disease monitoring, and measuring the safety or toxicity of treatments or environmental exposures. This broad utility is driving substantial market growth.
Recent developments in the market include:
In November 2022, Biocare Medical acquired Empire Genomics, enhancing its capabilities in innovative, automated immunohistochemistry (IHC) and FISH instrumentation and reagents. In October 2023, Thermo Fisher Scientific acquired Olink, a leader in next-generation proteomics. In July 2023, BioNTech completed the acquisition of InstaDeep. In December 2023, Xlife Sciences AG announced a cooperation with Quant Biomarkers AG for developing advanced biomarkers for kidney diseases.
Key Insights North America holds the largest market share. The safety biomarkers segment accounts for the largest share by type. The drug discovery and development segment dominates the market by application. The cancer segment captures the highest market share by disease.
Regional Overview North America is the leading region in the biomarkers market, with a strong focus on cancer biomarkers—genes, proteins, or other substances that provide critical insights into an individual's cancer. The region's diverse population, including significant Mexican Indigenous (MI) and Mexican Mestizo (MM) groups, highlights the need for specialized pharmacogenetic studies. The Asia-Pacific region is poised for rapid growth in the biomarkers market, driven by the need to diagnose and manage serious infections like sepsis, which remains a prevalent cause of morbidity and mortality in resource-limited settings such as India. In China, the China Health and Retirement Longitudinal Study (CHARLS) has included blood biomarkers, marking a significant advancement in the country's healthcare system.
Report Highlights By Type
The Safety Biomarkers segment has captured the prime market share in the global biomarkers market by type, reflecting their critical importance in medical interventions and environmental exposures. These biomarkers are indispensable for detecting or predicting adverse drug effects or exposure-related toxicity, often signaling necessary dose modifications. Safety biomarkers can identify patients at significant safety risk, thereby preventing the initiation of potentially harmful therapies. As regulatory agencies increasingly accept and qualify these biomarkers, their implementation in early clinical trials will expand, playing a pivotal role in decision-making processes. This will facilitate the seamless progression of promising therapeutics from preclinical stages through to clinical development, underscoring the segment's significant impact on advancing safe and effective medical treatments.
By Disease
Cancer is projected to dominate the disease segment of the biomarkers market, driven by the unique biomarker patterns each individual's cancer exhibits. These biomarkers significantly influence the effectiveness of various cancer treatments, aiding patients and doctors in selecting the most appropriate therapeutic options. Biomarker testing, applicable to both solid tumors and blood cancers, assists in diagnosing, monitoring, and managing cancer throughout and after treatment. The diverse applications of biomarkers in oncology encompass risk assessment, screening, differential diagnosis, prognosis determination, treatment response prediction, and disease progression monitoring. Given their critical role at every disease stage, rigorous evaluation, including analytical and clinical validation and clinical utility assessment, is essential before incorporating biomarkers into routine clinical care, ensuring their efficacy and reliability in oncology.
In January 2023, Agilent announced the acquisition of Avida Biomed, a developer of high-performance NGS target enrichment workflows for cancer research.
By Applications
Drug Discovery and Development is projected to dominate the application segment of the biomarkers market revenue. Biomarkers play a pivotal role in characterizing patient populations, quantifying the extent to which new drugs reach their intended targets, altering pathophysiological mechanisms, and achieving clinical outcomes. In genomics, the primary challenge is to identify unique molecular signatures in complex biological mixtures that correlate with biological events, thereby validating novel drug targets and predicting drug responses. Biomarkers enable the stratification of patient populations and the quantification of drug benefits in primary prevention or disease-modification studies, particularly in underserved areas like neurodegeneration and cancer. Clinically useful biomarkers are essential for informing regulatory and therapeutic decision-making regarding candidate drugs and their indications, expediting the process of bringing new medicines to the right patients efficiently.
Market Dynamics Drivers:
Advantages of Biomarkers as Surrogate Endpoints
Advantages of Biomarkers as Surrogate Endpoints: Biomarkers serve as surrogate endpoints in clinical trials, offering interim evidence on treatment safety and efficacy. They help design smaller, more efficient studies, reducing the number of subjects exposed to experimental treatments.
Restraints:
Challenges in Biomarker Evaluation
Challenges in Biomarker Evaluation: The diverse procedures used for sample collection, storage, and analysis, along with the need for stringent handling protocols, pose significant challenges to the reliability and reproducibility of biomarker data.
Opportunities:
Expanding Applications of Biomarkers
Expanding Applications of Biomarkers: The future of biomarkers in clinical practice is promising, with growing applications in disease diagnosis, personalized treatment guidance, and prognostic predictions. Advances in genetic analysis and omics technologies are paving the way for new biomarker discoveries.
Recent Developments
In September 2022, KCAS expanded its presence by acquiring France-based Active Biomarkers.
In October 2023, Thermo Fisher Scientific acquired Olink. Key Players in the Biomarkers Market
Key players in the biomarkers market include:
Bio-Rad Laboratories, Inc. Qiagen Epigenomics AG Abbott Hoffmann-La Roche Ltd. Agilent Technologies, Inc. Johnson & Johnson Services, Inc. Siemens Thermo Fisher Scientific, Inc.
Market Segmentation By Type Validation Efficacy Safety
By Disease Neurological Diseases Cancer Immunological Diseases Cardiovascular Diseases Others
By Application Personalized Medicines Drug Discovery & Development Diagnostics Others
By Geography North America U.S. Canada Europe Germany France United Kingdom Rest of Europe
Asia Pacific China Japan India Southeast Asia Rest of Asia Pacific
Latin America Brazil Rest of Latin America
Middle East & Africa (MEA) GCC North Africa South Africa Rest of Middle East & Africa
Table of content 1. Introduction 1.1. Report Description 1.2. Research Methodology 1.2.1. Data Mining 1.2.2. Market Modeling and Forecasting 1.2.3. Data Validation 1.2.4. Industry Analysis
5.4. Others 5.4.1. Others Market Size and Growth Rate (2021-2030)
6. Biomarkers Market by Application 6.1. Introduction 6.2. Biomarkers Market Size and Growth Rate by Application (2021-2030) 6.3. Personalized Medicines 6.3.1. Personalized Medicines Market Size and Growth Rate (2021-2030) 6.4. Drug Discovery & Development 6.4.1. Drug Discovery & Development Market Size and Growth Rate (2021-2030) 6.5. Diagnostics 6.5.1 Diagnostics Market Size and Growth Rate (2021-2030) 6.6. Others 6.6.1 Others Market Size and Growth Rate (2021-2030)
10. Company Profiles 10.1. Bio-Rad Laboratories, Inc. 10.1.1. Business Overview 10.1.2. Service Portfolio 10.1.3. Strategic Developments 10.1.4. Financial Overview
10.2. Qiagen 10.2.1. Business Overview 10.2.2. Service Portfolio 10.2.3. Strategic Developments 10.2.4. Financial Overview
10.3. Epigenomics AG 10.3.1. Business Overview 10.3.2. Service Portfolio 10.3.3. Strategic Developments 10.3.4. Financial Overview
10.4. Abbott 10.4.1. Business Overview 10.4.2. Service Portfolio 10.4.3. Strategic Developments 10.4.4. Financial Overview
10.5. Hoffmann-La Roche Ltd. 10.5.1. Business Overview 10.5.2. Service Portfolio 10.5.3. Strategic Developments 10.5.4. Financial Overview
10.6. Agilent Technologies, Inc. 10.6.1. Business Overview 10.6.2. Service Portfolio 10.6.3. Strategic Developments 10.6.4. Financial Overview
10.7. Johnson & Johnson Services, Inc. 10.7.1. Business Overview 10.7.2. Service Portfolio 10.7.3. Strategic Developments 10.7.4. Financial Overview
10.8. Siemens 10.8.1. Business Overview 10.8.2. Service Portfolio 10.8.3. Strategic Developments 10.8.4. Financial Overview
10.9. Thermo Fisher Scientific, Inc. 10.9.1. Business Overview 10.9.2. Service Portfolio 10.9.3. Strategic Developments 10.9.4. Financial Overview.
11. List of Tables and Figures Table Biomarkers Market Size and Market Share by Type (2021-2023) Table Biomarkers Market Size and Market Share by Type (2023-2030) Figure Contract Manufacturing Market Size and Growth Rate (2021-2030) Figure Process Development Market Size and Growth Rate (2021-2030) Figure Upstream Market Size and Growth Rate (2021-2030) Figure Downstream Market Size and Growth Rate (2021-2030) Figure Fill & Finish Operations Market Size and Growth Rate (2021-2030) Figure Analytical & QC studies Market Size and Growth Rate (2021-2030) Figure Packaging Market Size and Growth Rate (2021-2030) Figure Contract Research Market Size and Growth Rate (2021-2030) Figure Inflammation & Immunology Market Size and Growth Rate (2021-2030) Figure Cardiology Market Size and Growth Rate (2021-2030) Figure Oncology Market Size and Growth Rate (2021-2030) Figure Neuroscience Market Size and Growth Rate (2021-2030) Figure Others Market Size and Growth Rate (2021-2030)
Table Biomarkers Market Size and Market Share by Disease (2021-2023) Table Biomarkers Market Size and Market Share by Disease (2023-2030) Figure Mammalian Market Size and Growth Rate (2021-2030) Figure Non-Mammalian Market Size and Growth Rate (2021-2030)
Table Biomarkers Market Size and Market Share by Application (2021-2023) Table Biomarkers Market Size and Market Share by Application (2023-2030) Figure Biologics Market Size and Growth Rate (2021-2030) Figure Vaccines Market Size and Growth Rate (2021-2030) Figure Monoclonal antibodies (MABs) Market Size and Growth Rate (2021-2030) Figure Recombinant Proteins Market Size and Growth Rate (2021-2030) Figure Antisense, RNAi, & Molecular Therapy Market Size and Growth Rate (2021-2030) Figure Others Market Size and Growth Rate (2021-2030)
Table Biomarkers Market by Regions (2021-2023) Table Biomarkers Market by Regions (2023-2030) Figure North America Biomarkers Market Size and Growth Rate (2021-2030) Table North America Biomarkers Market by Type (2021-2023) Table North America Biomarkers Market by Type (2023-2030) Table North America Biomarkers by Source (2021-2023) Table North America Biomarkers by Source (2023-2030) Table North America Biomarkers by Application (2021-2023) Table North America Biomarkers by Application (2023-2030) Figure United States Biomarkers Market Size and Growth Rate (2021-2030) Table United States Biomarkers Market by Type (2021-2023) Table United States Biomarkers Market by Type (2023-2030) Table United States Biomarkers by Source (2021-2023) Table United States Biomarkers by Source (2023-2030) Figure Canada Biomarkers Market Size and Growth Rate (2021-2030) Table Canada Biomarkers Market by Type (2021-2023) Table Canada Biomarkers Market by Type (2023-2030) Table Canada Biomarkers by Source (2021-2023) Table Canada Biomarkers by Source (2023-2030) Figure Europe Biomarkers Market Size and Growth Rate (2021-2030) Table Europe Biomarkers Market by Type (2021-2023) Table Europe Biomarkers Market by Type (2023-2030) Table Europe Biomarkers by Source (2021-2023) Table Europe Biomarkers by Source (2023-2030) Table Europe Biomarkers by Application (2021-2023) Table Europe Biomarkers by Application (2023-2030) Figure Germany Biomarkers Market Size and Growth Rate (2021-2030) Table Germany Biomarkers Market by Type (2021-2023) Table Germany Biomarkers Market by Type (2023-2030) Table Germany Biomarkers by Source (2021-2023) Table Germany Biomarkers by Source (2023-2030) Figure France Biomarkers Market Size and Growth Rate (2021-2030) Table France Biomarkers Market by Type (2021-2023) Table France Biomarkers Market by Type (2023-2030) Table France Biomarkers by Source (2021-2023) Table France Biomarkers by Source (2023-2030) Figure UK Biomarkers Market Size and Growth Rate (2021-2030) Table UK Biomarkers Market by Type (2021-2023) Table UK Biomarkers Market by Type (2023-2030) Table UK Biomarkers by Source (2021-2023) Table UK Biomarkers by Source (2023-2030) Figure Russia Biomarkers Market Size and Growth Rate (2021-2030) Table Russia Biomarkers Market by Type (2021-2023) Table Russia Biomarkers Market by Type (2023-2030) Table Russia Biomarkers by Source (2021-2023) Table Russia Biomarkers by Source (2023-2030) Figure Italy Biomarkers Market Size and Growth Rate (2021-2030) Table Italy Biomarkers Market by Type (2021-2023) Table Italy Biomarkers Market by Type (2023-2030) Table Italy Biomarkers by Source (2021-2023) Table Italy Biomarkers by Source (2023-2030) Figure Rest of Europe Biomarkers Market Size and Growth Rate (2021-2030) Table Rest of Europe Biomarkers Market by Type (2021-2023) Table Rest of Europe Biomarkers Market by Type (2023-2030) Table Rest of Europe Biomarkers by Source (2021-2023) Table Rest of Europe Biomarkers by Source (2023-2030) Figure Asia-Pacific Biomarkers Market Size and Growth Rate (2021-2030) Table Asia-Pacific Biomarkers Market by Type (2021-2023) Table Asia-Pacific Biomarkers Market by Type (2023-2030) Table Asia-Pacific Biomarkers by Source (2021-2023) Table Asia-Pacific Biomarkers by Source (2023-2030) Table Asia-Pacific Biomarkers by Application (2021-2023) Table Asia-Pacific Biomarkers by Application (2023-2030) Figure China Biomarkers Market Size and Growth Rate (2021-2030) Table China Biomarkers Market by Type (2021-2023) Table China Biomarkers Market by Type (2023-2030) Table China Biomarkers by Source (2021-2023) Table China Biomarkers by Source (2023-2030) Figure Japan Biomarkers Market Size and Growth Rate (2021-2030) Table Japan Biomarkers Market by Type (2021-2023) Table Japan Biomarkers Market by Type (2023-2030) Table Japan Biomarkers by Source (2021-2023) Table Japan Biomarkers by Source (2023-2030) Figure India Biomarkers Market Size and Growth Rate (2021-2030) Table India Biomarkers Market by Type (2021-2023) Table India Biomarkers Market by Type (2023-2030) Table India Biomarkers by Source (2021-2023) Table India Biomarkers by Source (2023-2030) Figure Southeast Asia Biomarkers Market Size and Growth Rate (2021-2030) Table Southeast Asia Biomarkers Market by Type (2021-2023) Table Southeast Asia Biomarkers Market by Type (2023-2030) Table Southeast Asia Biomarkers by Source (2021-2023) Table Southeast Asia Biomarkers by Source (2023-2030) Figure Rest of Asia-Pacific Biomarkers Market Size and Growth Rate (2021-2030) Table Rest of Asia-Pacific Biomarkers Market by Type (2021-2023) Table Rest of Asia-Pacific Biomarkers Market by Type (2023-2030) Table Rest of Asia-Pacific Biomarkers by Source (2021-2023) Table Rest of Asia-Pacific Biomarkers by Source (2023-2030) Figure South America Biomarkers Market Size and Growth Rate (2021-2030) Table South America Biomarkers Market by Type (2021-2023) Table South America Biomarkers Market by Type (2023-2030) Table South America Biomarkers by Source (2021-2023) Table South America Biomarkers by Source (2023-2030) Table South America Biomarkers by Application (2021-2023) Table South America Biomarkers by Application (2023-2030) Figure Brazil Biomarkers Market Size and Growth Rate (2021-2030) Table Brazil Biomarkers Market by Type (2021-2023) Table Brazil Biomarkers Market by Type (2023-2030) Table Brazil Biomarkers by Source (2021-2023) Table Brazil Biomarkers by Source (2023-2030) Figure Mexico Biomarkers Market Size and Growth Rate (2021-2030) Table Mexico Biomarkers Market by Type (2021-2023) Table Mexico Biomarkers Market by Type (2023-2030) Table Mexico Biomarkers by Source (2021-2023) Table Mexico Biomarkers by Source (2023-2030) Figure Columbia Biomarkers Market Size and Growth Rate (2021-2030) Table Columbia Biomarkers Market by Type (2021-2023) Table Columbia Biomarkers Market by Type (2023-2030) Table Columbia Biomarkers by Source (2021-2023) Table Columbia Biomarkers by Source (2023-2030) Figure Rest of South America Biomarkers Market Size and Growth Rate (2021-2030) Table Rest of South America Biomarkers Market by Type (2021-2023) Table Rest of South America Biomarkers Market by Type (2023-2030) Table Rest of South America Biomarkers by Source (2021-2023) Table Rest of South America Biomarkers by Source (2023-2030) Figure Middle East and Africa Biomarkers Market Size and Growth Rate (2021-2030) Table Middle East and Africa Biomarkers Market by Type (2021-2023) Table Middle East and Africa Biomarkers Market by Type (2023-2030) Table Middle East and Africa Biomarkers by Source (2021-2023) Table Middle East and Africa Biomarkers by Application (2021-2023) Table Middle East and Africa Biomarkers by Application (2023-2030) Figure Saudi Arabia Biomarkers Market Size and Growth Rate (2021-2030) Table Saudi Arabia Biomarkers Market by Type (2021-2023) Table Saudi Arabia Biomarkers Market by Type (2023-2030) Table Saudi Arabia Biomarkers by Source (2021-2023) Table Saudi Arabia Biomarkers by Source (2023-2030) Figure United Arab Emirates Biomarkers Market Size and Growth Rate (2021-2030) Table United Arab Emirates Biomarkers Market by Type (2021-2023) Table United Arab Emirates Biomarkers Market by Type (2023-2030) Table United Arab Emirates Biomarkers by Source (2021-2023) Table United Arab Emirates Biomarkers by Source (2023-2030) Figure South Africa Biomarkers Market Size and Growth Rate (2021-2030) Table South Africa Biomarkers Market by Type (2021-2023) Table South Africa Biomarkers Market by Type (2023-2030) Table South Africa Biomarkers by Source (2021-2023) Table South Africa Biomarkers by Source (2023-2030) Figure Rest of Middle East and Africa Biomarkers Market Size and Growth Rate (2021-2030) Table Rest of Middle East and Africa Biomarkers Market by Type (2021-2023) Table Rest of Middle East and Africa Biomarkers Market by Type (2023-2030) Table Rest of Middle East and Africa Biomarkers by Source (2021-2023) Table Rest of Middle East and Africa Biomarkers by Source (2023-2030)
The process of market research at Ultra Market Research is an iterative in application and usually follows following path. Information from secondary used to build data models, then results from data models are validated from primary participants. Then cycle repeats where, according to inputs from primary participants, additional secondary research is done and new Information is again incorporated into data model. The process continues till desired level of Information is not generated
To calculate the market size, the report considers the revenue generated from the sales of Ultra Market Research providers. The revenue generated from the sales of Ultra Market Research has been calculated through primary and secondary research. The report also presents the key players operating in the Ultra Market Research market across the globe identified through secondary research and a corresponding detailed analysis of the top vendors in the market. The market size calculation also includes distribution channel segmentation determined using secondary sources and verified through primary sources.
Secondary Research
The secondary research source that are typically referred to include, but are not limited to:
Company websites, annual reports, financial reports, broker reports, investor presentations and SEC filings
Internal and external proprietary databases, relevant patent and regulatory databases
National government documents, statistical databases and market reports
News articles, press releases and web-casts specific to the companies operating in the market
The source for secondary research includes but is not limited to: Factiva, Hoovers and Statista
Inner Circle Represents – Stage of Research Process
Middle Circle Represents – Source of Information
Outer Circle Represents – Information Derived from that source
Primary Research We conduct primary interviews on an ongoing basis with industry participants and commentators in order to validate data and analysis. A typical research interview fulfills the following functions:
It provides first-hand Information on the market size, market trends, growth trends, competitive landscape, future outlook etc.
Helps in validating and strengthening the secondary research findings
Further develops the analysis team’s expertise and market understanding
Primary research involves E-mail interactions, telephonic interviews as well as face-to-face interviews for each market, category, segment and sub-segment across geographies
The participants who typically take part in such a process include, but are not limited to:
Industry participants: CEOs, VPs, marketing/ distribution channel managers, market intelligence managers and national sales managers
Purchasing managers, technical personnel, distributors and resellers
Outside experts: Investment bankers, valuation experts, research analysts specializing in specific markets
Key opinion leaders specializing in different areas corresponding to different industry distribution channels
Models Where no hard data is available, we use modeling and estimates in order to produce comprehensive data sets. A rigorous methodology is adopted in which the available hard data is cross referenced with the following data distribution channels to produce estimates:
Demographic data: Population split by segment
Macro-economic indicators: GDP, etc.
Industry indicators: Expenditure, distribution channel stage & infrastructure, sector growth and facilities.
Data is then cross checked by the expert panel.
2..1 Company Share Analysis Model
Company share analysis is used to derive the size of Global market. As well as study of revenues of companies for last three to five years also provide the base for forecasting the market size and its growth rate. This model is built in following steps: 2..2 Revenue Based Modeling
Revenue based models can be built in two ways – Top-Down or Bottom-Up irrespective of industry. Market size estimated from company share analysis acts as a validation point for bottom-up approach where as it acts as starting point for top-down approach.
2.1 Research Limitations Inflation is not a part of pricing in this report. Prices of Biomarkers and its derivatives vary in each region and hence similar revenue ratio does not follow for each individual region. The same price for each distribution channel has been taken into account while estimating and forecasting market revenue Globally. Regional average price has been considered while breaking down this market by application in each region. This report provides market size of Global Biomarkers for the past year and forecasts for the next six years. Global Biomarkers Market size is given in terms of revenue. Market revenue is defined in USD Million. Market numbers are given on the basis of different Biomarkers categories. Market size and forecasts for each major application is provided in the context of Global market. The numbers provided in this report are derived on the basis of demand for Biomarkers from different application industries in different regions.
Market Segmentation By Type Validation Efficacy Safety
By Disease Neurological Diseases Cancer Immunological Diseases Cardiovascular Diseases Others
By Application Personalized Medicines Drug Discovery & Development Diagnostics Others
By Geography North America U.S. Canada Europe Germany France United Kingdom Rest of Europe
Asia Pacific China Japan India Southeast Asia Rest of Asia Pacific
Latin America Brazil Rest of Latin America
Middle East & Africa (MEA) GCC North Africa South Africa Rest of Middle East & Africa
